Patrick Ha, MD

Professor of Clinical X
Otolaryngology
+1 415 885-7528

Patrick Ha, MD is a Professor and the Chief of Head and Neck Oncologic Surgery in the Department of Otolaryngology – Head and Neck Surgery (OHNS) at the University of California, San Francisco. He also holds the Irwin Mark Jacobs and Joan Klein Jacobs Distinguished Professorship in Head and Neck Surgery, and he has been appointed Medical Director of the Mission Bay Adult Cancer Services. After graduating magna cum laude from Harvard University, he received his medical degree from The Johns Hopkins School of Medicine in Baltimore, Maryland. Dr. Ha completed his one-year internship at The Johns Hopkins Hospital, Baltimore, Maryland, and he also completed an otolaryngology residency from the same institution, followed by advanced training in head and neck surgery at The Johns Hopkins Hospital. Prior to joining UCSF’s Department of OHNS, Dr. Ha was a clinician scientist and an associate professor on the full time faculty at Johns Hopkins working at the Greater Baltimore Medical Center.

Dr. Ha’s clinical expertise covers the full breadth of head and neck surgery, including a focus on thyroid and parathyroid surgery, as well as endoscopic laser and transoral robotic approaches for throat cancers. His current area of research is focused on the molecular changes occurring in salivary gland adenoid cystic carcinoma as well as head and neck squamous cell carcinoma, and he has held multiple NIH grants focused on studying these mechanisms. In addition, he serves on the editorial board of several journals including Head and Neck and Oral Oncology. He has over 90 published journal articles. While at Johns Hopkins, he held the role of associate residency program director and won several teaching awards for his work with medical students and residents.

Publications: 

Operational classification of cutaneous squamous cell carcinomas based on unsupervised clustering of real cases by experts.

Journal of the European Academy of Dermatology and Venereology : JEADV

Gaudy-Marqueste C, Grob JJ, Garbe C, Ascierto PA, Arron S, Basset-Seguin N, Bohne AS, Lenoir C, Dummer R, Fargnoli MC, Guminski A, Hauschild A, Kaufmann R, Lallas A, Del Marmol V, Migden M, Penicaud M, Rembielak A, Stratigos A, Tagliaferri L, Zalaudek I, Arance A, Badinand D, Bossi P, Challapalli A, Clementi M, Di Stefani A, Ferrándiz-Pulido C, Giuffrida R, Gravina GL, Ha P, Heinzerling L, Mallet S, Paradisi A, Mohr P, Piccerillo A, Rutkowski D, Saiag P, Sollena P, Trakatelli M, Wojcieszek P, Yom SS, Zelin E, Peris K, Malvehy J

68Ga-FAP-2286 PET of Solid Tumors: Biodistribution, Dosimetry, and Comparison with 18F-FDG.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Kline B, Yadav S, Seo Y, Ippisch RC, Castillo J, Aggarwal RR, Kelley RK, Behr SC, Flavell RR, Lawhn-Heath C, Melisko M, Rugo HS, Wang V, Yom SS, Ha P, Jiang F, Hope TA

Rate of occult metastasis in lip squamous cell carcinoma: A systematic review and meta-analysis.

Head & neck

Kansara S, Oral E, Sarkar I, Sandulache V, Mualla R, Walvekar RR, Ryan W, Ha P

The tumor microenvironment of benign and malignant salivary gland tumors.

Head & neck

Wai KC, Okholm TLH, Ha PK, Marquez DM, Tenvooren I, Jones KB, Spitzer MH

Postoperative inpatient surgical complications following head and neck microvascular free tissue transfer.

Head & neck

Abdulbaki H, Ha PK, Knott PD, Park AM, Seth R, Heaton CM, Wai KC

Prognostic risk factors of buccal squamous cell carcinoma: A case-control study.

Head & neck

Callander JK, Souza SS, Eltawil Y, El-Sayed IH, George JR, Ha P, Ryan WR, Xu MJ, Heaton CM

International consensus statement on allergy and rhinology: Sinonasal tumors.

International forum of allergy & rhinology

Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Tos APD, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meço C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN

Circulating tumor HPV DNA assessments after surgery for human papilloma virus-associated oropharynx carcinoma.

American journal of otolaryngology

Souza SS, Stephens EM, Bourdillon AT, Bhethanabotla R, Farzal Z, Plonowska-Hirshfeld K, Qualliotine JR, Heaton CM, Ha PK, Ryan WR

The neutrophil-to-lymphocyte ratio in salivary gland cancers treated with pembrolizumab.

Head & neck

Lee RH, Truong A, Wu X, Kang H, Algazi AP, El-Sayed IH, George JR, Heaton CM, Ryan WR, Ha PK, Wai KC

Treatment Modality Impact on Patient-Reported Quality of Life in Human Papilloma Virus-Associated Oropharyngeal Carcinoma.

The Laryngoscope

Plonowska-Hirschfeld KA, Gulati A, Stephens EM, Ochoa E, Xu MJ, Ha PK, Heaton CM, Yom SS, Chan JW, Algazi A, Kang H, Ryan WR

Transcriptional space-time mapping identifies concerted immune and stromal cell patterns and gene programs in wound healing and cancer.

Cell stem cell

Hu KH, Kuhn NF, Courau T, Tsui J, Samad B, Ha P, Kratz JR, Combes AJ, Krummel MF

A prospective evaluation of neck and shoulder function following treatments of early-stage human papillomavirus-associated oropharynx cancer.

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

Gulati A, Plonowska-Hirschfeld K, Stephens EM, Kansara S, Zebolsky AL, Ochoa E, Xu MJ, Ha PK, Heaton CM, Yom SS, Chan JW, Algazi AP, Kang H, Ryan WR

Prospective quality of life outcomes for human papillomavirus associated oropharynx cancer patients after surgery alone.

American journal of otolaryngology

Stephens EM, Plonowska-Hirschfeld K, Gulati A, Kansara S, Qualliotine J, Zelbolsky AL, van Zante A, Ha PK, Heaton CM, Ryan WR

Dynamic CD8+ T�cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes.

Cell

Rahim MK, Okholm TLH, Jones KB, McCarthy EE, Liu CC, Yee JL, Tamaki SJ, Marquez DM, Tenvooren I, Wai K, Cheung A, Davidson BR, Johri V, Samad B, O'Gorman WE, Krummel MF, van Zante A, Combes AJ, Angelo M, Fong L, Algazi AP, Ha P, Spitzer MH

Patterns of Postoperative Trismus Following Mandibulectomy and Fibula Free Flap Reconstruction.

Cancers

Lee RH, Evans C, Laus J, Sanchez C, Wai KC, Knott PD, Seth R, El-Sayed IH, George JR, Ryan WR, Heaton CM, Park AM, Ha PK

Relations of Current and Past Cancer with Severe Outcomes among 104,590 Hospitalized COVID-19 Patients: The COVID EHR Cohort at the University of Wisconsin.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Nolan MB, Piasecki TM, Smith SS, Baker TB, Fiore MC, Adsit RT, Bolt DM, Conner KL, Bernstein SL, Eng OD, Lazuk D, Gonzalez A, Hayes-Birchler T, Jorenby DE, D'Angelo H, Kirsch JA, Williams BS, Kent S, Kim H, Lubanski SA, Yu M, Suk Y, Cai Y, Kashyap N, Mathew J, McMahan G, Rolland B, Tindle HA, Warren GW, Abu-El-Rub N, An LC, Boyd AD, Brunzell DH, Carrillo VA, Chen LS, Davis JM, Deshmukh VG, Dilip D, Goldstein AO, Ha PK, Iturrate E, Jose T, Khanna N, King A, Klass E, Lui M, Mermelstein RJ, Poon C, Tong E, Wilson KM, Theobald WE, Slutske WS

Human Papillomavirus-Associated Head and Neck Malignancies in Sub-Saharan Africa: A Systematic Review.

JCO global oncology

Okerosi S, Mokoh LW, Rubagumya F, Niyibizi BA, Nkya A, Van Loon K, Buckle G, Bent S, Ha P, Fagan JJ, Ng D, Aswani J, Xu MJ

Approaches to the Management of Metastatic Adenoid Cystic Carcinoma.

Cancers

Lee RH, Wai KC, Chan JW, Ha PK, Kang H

STAT3 Activation as a Predictive Biomarker for Ruxolitinib Response in Head and Neck Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Qureshy Z, Li H, Zeng Y, Rivera J, Cheng N, Peterson CN, Kim MO, Ryan WR, Ha PK, Bauman JE, Wang SJ, Long SR, Johnson DE, Grandis JR

De-intensification Strategies for Head and Neck Cancer.

Madeleine P. Strohl, Patrick K. Ha, Kaveh Zakeri, Nancy Lee

Longitudinal Analysis of Swallowing Displacement Kinematics After Oropharyngeal Cancer Treatment.

The Laryngoscope

Kidane J, Laus J, Gulati A, Gochman GE, Schneider SL, Chan JW, Yom SS, Ha P, Boscardin WJ, Ryan WR, Ma Y

Abstract LB084: AXL as a therapeutic target in adenoid cystic carcinoma: preclinical evaluation of AXL targeting antibody-drug conjugate (ADCT-601).

Cancer research

Joseph O. Humtsoe, Leilani Jones, Shorook Naara, Francesca Zammarchi, Nicole Spardy Burr, Patrick H. van Berkel, Patrick K. Ha, Hyunseok Kang

Development and Characterization of MYB-NFIB Fusion Expression in Adenoid Cystic Carcinoma.

Cancers

Humtsoe JO, Kim HS, Jones L, Cevallos J, Boileau P, Kuo F, Morris LGT, Ha P

Validation of anti-correlated TGFβ signaling and alternative end-joining DNA repair signatures that predict response to genotoxic cancer therapy.

Clinical cancer research : an official journal of the American Association for Cancer Research

Guix I, Liu Q, Pujana MA, Ha P, Piulats J, Linares I, Guedea F, Mao JH, Lazar A, Chapman J, Yom SS, Ashworth A, Barcellos-Hoff MH

Prevalence of human papillomavirus in head and neck cancers at tertiary care centers in the United States over time.

Cancer

Scott-Wittenborn N, D'Souza G, Tewari S, Rooper L, Troy T, Drake V, Bigelow EO, Windon MJ, Ryan WR, Ha PK, Kiess AP, Miles B, Westra WH, Mydlarz WK, Eisele DW, Fakhry C

Discovering dominant tumor immune archetypes in a pan-cancer census.

Cell

Combes AJ, Samad B, Tsui J, Chew NW, Yan P, Reeder GC, Kushnoor D, Shen A, Davidson B, Barczak AJ, Adkisson M, Edwards A, Naser M, Barry KC, Courau T, Hammoudi T, Argüello RJ, Rao AA, Olshen AB, Immunoprofiler Consortium, Cai C, Zhan J, Davis KC, Kelley RK, Chapman JS, Atreya CE, Patel A, Daud AI, Ha P, Diaz AA, Kratz JR, Collisson EA, Fragiadakis GK, Erle DJ, Boissonnas A, Asthana S, Chan V, Krummel MF

Adjuvant therapy improves survival in pT4aN0 oral cavity squamous cell carcinoma with bone invasion.

American journal of otolaryngology

Stanford-Moore GB, Sola AM, Chan J, El-Sayed I, George J, Ha P, Ryan WR, Heaton CM

Risk of Pathologic Extranodal Extension and Other Adverse Features After Transoral Robotic Surgery in Patients With HPV-Positive Oropharynx Cancer.

JAMA otolaryngology-- head & neck surgery

Zebolsky AL, George E, Gulati A, Wai KC, Carpenter P, Van Zante A, Ha PK, Heaton CM, Ryan WR

Phase 1/2a, open-label, multicenter study of RM-1929 photoimmunotherapy in patients with locoregional, recurrent head and neck squamous cell carcinoma.

Head & neck

Cognetti DM, Johnson JM, Curry JM, Kochuparambil ST, McDonald D, Mott F, Fidler MJ, Stenson K, Vasan NR, Razaq MA, Campana J, Ha P, Mann G, Ishida K, Garcia-Guzman M, Biel M, Gillenwater AM

Biologic and behavioral associations of estrogen receptor alpha positivity in head and neck squamous cell carcinoma.

Oral oncology

Drake V, Bigelow E, Fakhry C, Windon M, Rooper LM, Ha P, Miles B, Gourin C, Mandal R, Mydlarz W, London N, Vosler PS, Yavvari S, Troy T, Waterboer T, Eisele DW, D'Souza G

Impact of Smoking and Primary Tumor Subsite on Recurrence in HPV-Associated Oropharyngeal Squamous Cell Carcinoma.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Lee RH, Salesky M, Benjamin T, El-Sayed IH, George JR, Ha PK, Ryan WR, Heaton CM

RTOG-0129 risk groups are reproducible in a prospective multicenter heterogeneously treated cohort.

Cancer

Fakhry C, Tewari SR, Zhang L, Windon MJ, Bigelow EO, Drake VE, Rooper LM, Troy T, Ha P, Miles BA, Mydlarz WK, Eisele DW, D'Souza G

Molecular Markers that Matter in Salivary Malignancy.

Otolaryngologic clinics of North America

Wai KC, Kang H, Ha PK

A prospective study of patient-reported xerostomia-related outcomes after parotidectomy.

Laryngoscope investigative otolaryngology

Brodie KD, Zebolsky AL, Ochoa E, Ha PK, Heaton CM, El-Sayed IH, Ryan WR

Oncologic outcomes of human papillomavirus-associated oropharynx carcinoma treated with surgery alone: A 12-institution study of 344 patients.

Cancer

Ryan WR, Xu MJ, Ochoa E, Plonowska-Hirschfeld KA, Zebolsky AL, Ha PK, Bewley AF, Mallen-St Clair J, Joshi AS, Coffey CS, Faraji F, MacDonald BV, Houlton JJ, Gobillot TA, Curry JM, Philips R, Hackman TG, Richmon JD, Holcomb AJ, Coughlin AM, Panwar A, Smith RB, Herberg ME, Fakhry C, Cognetti DM

Management of Salivary Gland Malignancy: ASCO Guideline.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

MYB RNA In Situ Hybridization Facilitates Sensitive and Specific Diagnosis of Adenoid Cystic Carcinoma Regardless of Translocation Status.

The American journal of surgical pathology

Rooper LM, Lombardo KA, Oliai BR, Ha PK, Bishop JA

Patient-Reported Outcomes of Split-Thickness Skin Grafts for Floor of Mouth Cancer Reconstruction.

ORL; journal for oto-rhino-laryngology and its related specialties

Nasogastric tube feeding after transoral robotic surgery for oropharynx carcinoma.

American journal of otolaryngology

Plonowska KA, Ochoa E, Zebolsky AL, Patel N, Hoppe KR, Ha PK, Heaton CM, Ryan WR

Timing, number, and type of sexual partners associated with risk of oropharyngeal cancer.

Cancer

Drake VE, Fakhry C, Windon MJ, Stewart CM, Akst L, Hillel A, Chien W, Ha P, Miles B, Gourin CG, Mandal R, Mydlarz WK, Rooper L, Troy T, Yavvari S, Waterboer T, Brenner N, Eisele DW, D'Souza G

Newly identified members of fibroblast growth factor receptor 1 splice variants engage in crosstalk with the AXL/AKT axis in salivary adenoid cystic carcinoma.

Cancer research

Humtsoe JO, Kim HS, Leonard B, Ling S, Keam B, Marchionni L, Afsari B, Considine M, Favorov AV, Fertig EJ, Kang H, Ha PK

Head and neck surgery during the coronavirus-19 pandemic: The University of California San Francisco experience.

Head & neck

Wai KC, Xu MJ, Lee RH, El-Sayed IH, George JR, Heaton CM, Knott PD, Park AM, Ryan WR, Seth R, Ha PK

PET/CT in Surgical Planning for Head and Neck Cancer.

Seminars in Nuclear Medicine

Strohl MP, Ha PK, Flavell RR, Yom SS

Clinicopathologic implications of Myb and Beta-catenin expression in adenoid cystic carcinoma.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

Park S, Vora M, van Zante A, Humtsoe J, Kim HS, Yom S, Agarwal S, Ha P

The Role of Age and Merkel Cell Polyomavirus in Oral Cavity Cancers.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Windon M, Fakhry C, Rooper L, Ha P, Schoppy D, Miles B, Koch W, Vosler P, Eisele D, D'Souza G

Abstract A27: Differential protein-interactome of MYB-NF1B fusion in adenoid cystic carcinoma.

Clinical Cancer Research

Joseph O. Humtsoe, Hyun-Su Kim, Margaret Soucheray, Danielle Swaney, Patrick K. Ha

Improved Tumor Control Related to Radiotherapy Technological Development for Hypopharyngeal Cancer.

The Laryngoscope

Susko MS, Lazar AA, Dhar S, Chan JW, Shiao SL, Chapman CH, Johnson J, Quivey JM, Ryan WR, Heaton CM, Ha PK, Yom SS

Patient-Reported Quality of Life After Resection With Primary Closure for Oral Tongue Carcinoma.

The Laryngoscope

Ochoa E, Larson AR, Han M, Webb KL, Stanford-Moore GB, El-Sayed IH, George JR, Ha PK, Heaton CM, Ryan WR

HPV-positive Squamous Cell Carcinoma of the Larynx, Oral Cavity, and Hypopharynx: Clinicopathologic Characterization With Recognition of a Novel Warty Variant.

The American journal of surgical pathology

Rooper LM, Windon MJ, Hernandez T, Miles B, Ha PK, Ryan WR, Van Zante A, Eisele DW, D'Souza G, Fakhry C, Westra WH

Risk Factors for Human Papillomavirus-Positive Nonoropharyngeal Squamous Cell Carcinoma.

International Journal of Radiation Oncology • Biology • Physics

M.J. Windon, G. D'Souza, T. Waterboer, L. Rooper, W.H. Westra, T. Troy, D.M. Pardoll, M. Tan, S. Yavvari, A.P. Kiess, B. Miles, W. Mydlarz, P. Ha, N. Bender, D. Eisele, C. Fakhry

Risk factors for human papillomavirus-positive nonoropharyngeal squamous cell carcinoma.

Head & neck

Windon MJ, D'Souza G, Waterboer T, Rooper L, Westra WH, Troy T, Pardoll D, Tan M, Yavvari S, Kiess AP, Miles B, Mydlarz WK, Ha PK, Bender N, Eisele DW, Fakhry C

Machine Learning for Predicting Complications in Head and Neck Microvascular Free Tissue Transfer.

The Laryngoscope

Formeister EJ, Baum R, Knott PD, Seth R, Ha P, Ryan W, El-Sayed I, George J, Larson A, Plonowska K, Heaton C

The Milan System for Reporting Salivary Gland Cytopathology.

AJSP Review and Reports

Annemieke van Zante, Patrick Ha, Marc Philippe Pusztaszeri

Distinct biomarker and behavioral profiles of human papillomavirus-related oropharynx cancer patients by age.

Oral oncology

Fakhry C, Waterboer T, Westra WH, Rooper LM, Windon M, Troy T, Koch W, Gourin CG, Bender N, Yavvari S, Kiess AP, Miles BA, Ryan WR, Ha PK, Eisele DW, D'Souza G

Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma.

The Journal of clinical investigation

Ho AS, Ochoa A, Jayakumaran G, Zehir A, Valero Mayor C, Tepe J, Makarov V, Dalin MG, He J, Bailey M, Montesion M, Ross JS, Miller VA, Chan L, Ganly I, Dogan S, Katabi N, Tsipouras P, Ha P, Agrawal N, Solit DB, Futreal PA, El Naggar AK, Reis-Filho JS, Weigelt B, Ho AL, Schultz N, Chan TA, Morris LG

Molecular Genetics of Salivary Gland Cancer.

Jon Mallen-St. Clair, Patrick Ha

Beyond Depth of Invasion: Adverse Pathologic Tumor Features in Early Oral Tongue Squamous Cell Carcinoma.

The Laryngoscope

Larson AR, Kemmer J, Formeister E, El-Sayed I, Ha P, George J, Ryan W, Chan E, Heaton C

Genome-wide investigation of intragenic DNA methylation identifies ZMIZ1 gene as a prognostic marker in glioblastoma and multiple cancer types.

International journal of cancer

Mathios D, Hwang T, Xia Y, Phallen J, Rui Y, See AP, Maxwell R, Belcaid Z, Casaos J, Burger PC, McDonald KL, Gallia GL, Cope L, Kai M, Brem H, Pardoll DM, Ha P, Green JJ, Velculescu VE, Bettegowda C, Park CK, Lim M

Publisher Correction: Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers.

Nature communications

Ando M, Saito Y, Xu G, Bui NQ, Medetgul-Ernar K, Pu M, Fisch K, Ren S, Sakai A, Fukusumi T, Liu C, Haft S, Pang J, Mark A, Gaykalova DA, Guo T, Favorov AV, Yegnasubramanian S, Fertig EJ, Ha P, Tamayo P, Yamasoba T, Ideker T, Messer K, Califano JA

Can Early Dental Extractions Reduce Delays in Postoperative Radiation for Patients With Advanced Oral Cavity Carcinoma?

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

Strohl MP, Chen JP, Ha PK, Seth R, Yom SS, Heaton CM

Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers.

Nature communications

Ando M, Saito Y, Xu G, Bui NQ, Medetgul-Ernar K, Pu M, Fisch K, Ren S, Sakai A, Fukusumi T, Liu C, Haft S, Pang J, Mark A, Gaykalova DA, Guo T, Favorov AV, Yegnasubramanian S, Fertig EJ, Ha P, Tamayo P, Yamasoba T, Ideker T, Messer K, Califano JA

Incidentally Detected Oropharyngeal Squamous Cell Carcinoma on 18F-Fluciclovine PET/CT.

Clinical nuclear medicine

Raghavan K, Wen KW, Small EJ, Ha P, Flavell RR

Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity.

Cell

Binnewies M, Mujal AM, Pollack JL, Combes AJ, Hardison EA, Barry KC, Tsui J, Ruhland MK, Kersten K, Abushawish MA, Spasic M, Giurintano JP, Chan V, Daud AI, Ha P, Ye CJ, Roberts EW, Krummel MF

Treatment modality impact on quality of life for human papillomavirus-associated oropharynx cancer.

The Laryngoscope

Xu MJ, Plonowska KA, Gurman ZR, Humphrey AK, Ha PK, Wang SJ, El-Sayed IH, Heaton CM, George JR, Yom SS, Algazi AP, Ryan WR

Papillary cystadenoma of the parotid gland: A case report.

World journal of clinical cases

Wang L, Zhang SK, Ma Y, Ha PK, Wang ZM

Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancer.

The Journal of experimental medicine

Hedberg ML, Peyser ND, Bauman JE, Gooding WE, Li H, Bhola NE, Zhu TR, Zeng Y, Brand TM, Kim MO, Jordan RCK, VandenBerg S, Olivas V, Bivona TG, Chiosea SI, Wang L, Mills GB, Johnson JT, Duvvuri U, Ferris RL, Ha P, Johnson DE, Grandis JR

Should Margin Sampling Be Obtained from the Specimen or from the Resection Bed in Oral Cavity Cancer?.

Difficult Decisions in Head and Neck Oncologic Surgery

Jonathan P. Giurintano, Patrick K. Ha

Socioeconomic disparities in a population of patients undergoing total thyroidectomy for benign disease.

Head & neck

Wu TJ, Ha PK, El-Sayed IH, George JR, Heaton CM, Ryan WR, Russell MD

Correction: Tadalafil Augments Tumor-specific Immunity in Patients with Head and Neck Squamous Cell Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Califano JA, Khan Z, Noonan KA, Rudraraju L, Zhang Z, Wang H, Goodman S, Gourin CG, Ha PK, Fakhry C, Saunders J, Levine M, Tang M, Neuner G, Richmon JD, Blanco R, Agrawal N, Koch WM, Marur S, Weed DT, Serafini P, Borrello I

Data Set for the Reporting of Carcinomas of the Major Salivary Glands: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting.

Archives of pathology & laboratory medicine

Seethala RR, Altemani A, Ferris RL, Fonseca I, Gnepp DR, Ha P, Nagao T, Skalova A, Stenman G, Thompson LDR

Human Papillomavirus-Associated Oropharyngeal Cancer: Patterns of Nodal Disease.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Plonowska KA, Strohl MP, Wang SJ, Ha PK, George JR, Heaton CM, El-Sayed IH, Mallen-St Clair J, Ryan WR

Effects of a Comprehensive Performance Improvement Strategy on Postoperative Adverse Events in Head and Neck Surgery.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Panuganti B, Qiu Y, Messing B, Lee G, Fakhry C, Blanco R, Ha P, Messer K, Califano JA

Subjugation of TGFß Signaling by Human Papilloma Virus in Head and Neck Squamous Cell Carcinoma Shifts DNA Repair from Homologous Recombination to Alternative End-Joining.

Clinical cancer research : an official journal of the American Association for Cancer Research

Liu Q, Ma L, Jones T, Palomero L, Pujana MA, Martinez-Ruiz H, Ha PK, Murnane J, Cuartas I, Seoane J, Baumann M, Linge A, Barcellos-Hoff MH

Abstract 2812: Status of TGFbeta signaling determines PARP inhibitor sensitivity in head and neck cancer.

Experimental and Molecular Therapeutics

Qi Liu, Lin Ma, Luis Palomero, Miquel Àngel Pujana, Trevor Jones, Patrick Ha, John Murnane, Mary Helen Barcellos-Hoff

A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments.

Nature medicine

Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, Ha PK, Ryan WR, Pollack JL, Samad B, Asthana S, Chan V, Krummel MF

Shorter interval between radiation therapy and salvage laryngopharyngeal surgery increases complication rates following microvascular free tissue transfer.

American journal of otolaryngology

Formeister EJ, Sean Alemi A, El-Sayed I, George JR, Ha P, Daniel Knott P, Ryan WR, Seth R, Tamplen ML, Heaton CM

Salivary Gland Malignancies.

Head and Neck Cancers

Cristina P. Rodriguez, Jessica L. Geiger, Jon Mallen-St. Clair, Patrick K. Ha, Sue S. Yom, Adam S. Garden, David J. Adelstein

Splice Expression Variation Analysis (SEVA) for Inter-tumor Heterogeneity of Gene Isoform Usage in Cancer.

Bioinformatics (Oxford, England)

Afsari B, Guo T, Considine M, Florea L, Kagohara LT, Stein-O'Brien GL, Kelley D, Flam E, Zambo KD, Ha PK, Geman D, Ochs MF, Califano JA, Gaykalova DA, Favorov AV, Fertig EJ

Biochemical Properties of a Decoy Oligodeoxynucleotide Inhibitor of STAT3 Transcription Factor.

International journal of molecular sciences

Lee DS, O'Keefe RA, Ha PK, Grandis JR, Johnson DE

Increasing prevalence of human papillomavirus-positive oropharyngeal cancers among older adults.

Cancer

Windon MJ, D'Souza G, Rettig EM, Westra WH, van Zante A, Wang SJ, Ryan WR, Mydlarz WK, Ha PK, Miles BA, Koch W, Gourin C, Eisele DW, Fakhry C

Mortality risk after clinical management of recurrent and metastatic adenoid cystic carcinoma.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

Xu MJ, Wu TJ, van Zante A, El-Sayed IH, Algazi AP, Ryan WR, Ha PK, Yom SS

Clinical PET/CT Imaging and Histopathology Demonstrate Expression of Prostate-Specific Membrane Antigen in Salivary Gland Adenoid Cystic Carcinomas.

International Journal of Radiation Oncology • Biology • Physics

A.P. Kiess, J. Bishop, H. Kang, S. Rowe, C. Shen, M. Brummet, D. Eisele, M. Brait Rodriguez, P. Ha, M.G. Pomper

Submandibular Gland Transfer: A Potential Imaging Pitfall.

AJNR. American journal of neuroradiology

Wu X, Yom SS, Ha PK, Heaton CM, Glastonbury CM

Prognostic factors for human papillomavirus-positive and negative oropharyngeal carcinomas.

The Laryngoscope

Yin LX, D'Souza G, Westra WH, Wang SJ, van Zante A, Zhang Y, Rettig EM, Ryan WR, Ha PK, Wentz A, Koch W, Eisele DW, Fakhry C

Abstract 17: Patterns of neck nodal metastases and recurrence in human papilloma virus-associated oropharyngeal squamous cell carcinoma after neck dissection.

Cancer Genomics and Signatures of Mutational Processes in Human Cancer

Madeleine P. Strohl, Steven J. Wang, Patrick K. Ha, Jonathan R. George, Chase M. Heaton, Ivan H. El-Sayed, Jon Mallen St Clair, William R. Ryan

Abstract 64: Abnormal splicing events in adenoid cystic carcinoma.

Novel Targets and Biomarkers in Head and Neck Cancer

Brandon Leonard, Joseph O. Humtsoe, Hyun-Su Kim, Shizhang Ling, Luigi Marchionni, Elana J. Fertig, Michael Considine, Patrick Ha

Prognostic Factors for Recurrence and Survival Independent of the Revised AJCC 8th Edition Staging System in Patients with Cutaneous Squamous Cell Carcinoma Treated with Multimodality Therapy.

International Journal of Radiation Oncology • Biology • Physics

M. Xu, A.A. Garsa, A. Lazar, S. Arron, W.R. Ryan, I. El-Sayed, J. George, A. Algazi, C. Heaton, P. Ha, S.S. Yom

A Novel Functional Splice Variant of AKT3 Defined by Analysis of Alternative Splice Expression in HPV-Positive Oropharyngeal Cancers.

Cancer research

Guo T, Sakai A, Afsari B, Considine M, Danilova L, Favorov AV, Yegnasubramanian S, Kelley DZ, Flam E, Ha PK, Khan Z, Wheelan SJ, Gutkind JS, Fertig EJ, Gaykalova DA, Califano J

Human papillomavirus tumour status is not associated with a positive depression screen for patients with oropharyngeal cancer.

The Journal of laryngology and otology

Qualliotine JR, Califano JA, Li RJ, Gold D, Messing B, Lee G, Ha P, Fakhry C

Molecular Genetics of Salivary Gland Cancer.

eLS

Jon Mallen-St. Clair, Patrick Ha

Abstract 1779: Chronic NSAID use increases survival in PIK3CA -altered head and neck squamous cell carcinoma.

Clinical Research (Excluding Clinical Trials)

Matthew Louis Hedberg, Noah Peyser, William Gooding, Hua Li, Toni Brand, Victor Olivas, Trever Bivona, Simion Choisea, Lin Wang, Jonas Johnson, Uma Duvvuri, Robert Ferris, Daniel Johnson, Patrick Ha, Julie Bauman, Jennifer Grandis

Abstract 3577: Splice expression variation analysis (SEVA) for differential gene isoform usage in cancer.

Bioinformatics and Systems Biology

Bahman Afsari, Theresa Guo, Michael Considine, Dylan Kelley, Emily Flam, Liliana Florea, Patrick Ha, Donald Geman, Michael F. Ochs, Joseph A. Califano, Daria A. Gaykalova, Alexander V. Favorov, Elana J. Fertig

(P069) Prognostic Factors for Recurrence and Survival Independent of the Revised AJCC 8th Edition Staging System in Patients With Cutaneous Squamous Cell Carcinoma.

International Journal of Radiation Oncology • Biology • Physics

Melody J. Xu, Adam A. Garsa, Ann Lazar, Sarah T. Arron, William R. Ryan, Ivan El-Sayed, Alain A. Algazi, Jonathan George, Patrick Ha, Sue S. Yom

Controversies in Postoperative Irradiation of Oropharyngeal Cancer After Transoral Surgery.

Surgical oncology clinics of North America

Yom SS, Mallen-St Clair J, Ha PK

The prognostic role of sex, race, and human papillomavirus in oropharyngeal and nonoropharyngeal head and neck squamous cell cancer.

Cancer

Fakhry C, Westra WH, Wang SJ, van Zante A, Zhang Y, Rettig E, Yin LX, Ryan WR, Ha PK, Wentz A, Koch W, Richmon JD, Eisele DW, D'Souza G

Differences in the Prevalence of Human Papillomavirus (HPV) in Head and Neck Squamous Cell Cancers by Sex, Race, Anatomic Tumor Site, and HPV Detection Method.

JAMA oncology

D'Souza G, Westra WH, Wang SJ, van Zante A, Wentz A, Kluz N, Rettig E, Ryan WR, Ha PK, Kang H, Bishop J, Quon H, Kiess AP, Richmon JD, Eisele DW, Fakhry C

Neutrophil-to-lymphocyte ratio: Prognostic indicator for head and neck squamous cell carcinoma.

Head & neck

Rosculet N, Zhou XC, Ha P, Tang M, Levine MA, Neuner G, Califano J

Adenoid cystic carcinoma: emerging role of translocations and gene fusions.

Oncotarget

Wysocki PT, Izumchenko E, Meir J, Ha PK, Sidransky D, Brait M

Patient experience and anxiety during and after treatment for an HPV-related oropharyngeal cancer.

Oral oncology

D'Souza G, Zhang Y, Merritt S, Gold D, Robbins HA, Buckman V, Gerber J, Eisele DW, Ha P, Califano J, Fakhry C

Abstract 3983: Highly sensitive detection of MYB-NFIB fusion transcripts in adenoid cystic carcinoma.

Clinical Research (Excluding Clinical Trials)

Piotr T. Wysocki, Shizhang Ling, Chunbo Shao, Marietta Tan, David Sidransky, Patrick Ha, Mariana Brait

Whole-Exome Sequencing of Salivary Gland Mucoepidermoid Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Kang H, Tan M, Bishop JA, Jones S, Sausen M, Ha PK, Agrawal N

Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screening.

International journal of oncology

Ling S, Rettig EM, Tan M, Chang X, Wang Z, Brait M, Bishop JA, Fertig EJ, Considine M, Wick MJ, Ha PK

Molecular Pathology and Biomarkers.

Advances in oto-rhino-laryngology

Ha PK, Stenman G

Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma.

Cancer prevention research (Philadelphia, Pa.)

Rettig EM, Talbot CC, Sausen M, Jones S, Bishop JA, Wood LD, Tokheim C, Niknafs N, Karchin R, Fertig EJ, Wheelan SJ, Marchionni L, Considine M, Fakhry C, Papadopoulos N, Kinzler KW, Vogelstein B, Ha PK, Agrawal N

Anatomy, Physiology, and Non-neoplastic Disorders of the Salivary Glands.

Sataloff’s Comprehensive Textbook of Otolaryngology: Head and Neck Surgery (Head and Neck Surgery) - Volume 5

Wojciech Mydlarz, Patrick Ha, David Eisele

Disease-free survival after salvage therapy for recurrent oropharyngeal squamous cell carcinoma.

Head & neck

Joseph AW, Guo T, Hur K, Xie Y, Yin L, Califano JA, Ha PK, Quon H, Richmon JD, Eisele DW, Agrawal N, Fakhry C

Personal characteristics of residents may predict competency improvement.

The Laryngoscope

Park E, Ha PK, Eisele DW, Francis HW, Kim YJ

Reduction of Pharyngocutaneous Fistulae in Laryngectomy Patients by a Comprehensive Performance Improvement Intervention.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Li RJ, Zhou XC, Fakhry C, Negrin J, Lee G, Ha P, Blanco R, Saunders J, Califano JA

Epigenetic screening of salivary gland mucoepidermoid carcinoma identifies hypomethylation of CLIC3 as a common alteration.

Oral oncology

Wang Z, Ling S, Rettig E, Sobel R, Tan M, Fertig EJ, Considine M, El-Naggar AK, Brait M, Fakhry C, Ha PK

Abstract 3839: Investigation of epigenetic based inter-tumoral heterogeneity identifies novel ZMIZ1 gene as a biomarker of cancer patient survival in multiple tumor types.

Cancer research

Dimitrios Mathios, Taeyoung Hwang, Jillian Phallen, Chetan Bettewgoda, Patrick Ha, Peter Burger, Henry Brem, Kerrie McDonald, Chul-Kee Park, Michael Lim

Retropharyngeal lymph node involvement in human papillomavirus-associated oropharyngeal squamous cell carcinoma.

The Laryngoscope

Baxter M, Chan JY, Mydlarz WK, Labruzzo SV, Kiess A, Ha PK, Aygun N, Agrawal N

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas.

Science translational medicine

Wang Y, Springer S, Mulvey CL, Silliman N, Schaefer J, Sausen M, James N, Rettig EM, Guo T, Pickering CR, Bishop JA, Chung CH, Califano JA, Eisele DW, Fakhry C, Gourin CG, Ha PK, Kang H, Kiess A, Koch WM, Myers JN, Quon H, Richmon JD, Sidransky D, Tufano RP, Westra WH, Bettegowda C, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Agrawal N

MYB rearrangement and clinicopathologic characteristics in head and neck adenoid cystic carcinoma.

The Laryngoscope

Rettig EM, Tan M, Ling S, Yonescu R, Bishop JA, Fakhry C, Ha PK

Surgical salvage improves overall survival for patients with HPV-positive and HPV-negative recurrent locoregional and distant metastatic oropharyngeal cancer.

Cancer

Guo T, Qualliotine JR, Ha PK, Califano JA, Kim Y, Saunders JR, Blanco RG, D'Souza G, Zhang Z, Chung CH, Kiess A, Gourin CG, Koch W, Richmon JD, Agrawal N, Eisele DW, Fakhry C

Tadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Califano JA, Khan Z, Noonan KA, Rudraraju L, Zhang Z, Wang H, Goodman S, Gourin CG, Ha PK, Fakhry C, Saunders J, Levine M, Tang M, Neuner G, Richmon JD, Blanco R, Agrawal N, Koch WM, Marur S, Weed DT, Serafini P, Borrello I

Pharyngocutaneous fistula after total laryngectomy: a single-institution experience, 2001-2012.

American journal of otolaryngology

Benson EM, Hirata RM, Thompson CB, Ha PK, Fakhry C, Saunders JR, Califano JA, Arnaoutakis D, Levine M, Tang M, Neuner G, Messing BP, Blanco RG

To "grow" or "go": TMEM16A expression as a switch between tumor growth and metastasis in SCCHN.

Clinical cancer research : an official journal of the American Association for Cancer Research

Shiwarski DJ, Shao C, Bill A, Kim J, Xiao D, Bertrand CA, Seethala RS, Sano D, Myers JN, Ha P, Grandis J, Gaither LA, Puthenveedu MA, Duvvuri U

The use of ultrasound in the search for the primary site of unknown primary head and neck squamous cell cancers.

Oral oncology

Fakhry C, Agrawal N, Califano J, Messing B, Liu J, Saunders J, Ha P, Coquia S, Hamper U, Gillison M, Blanco R

Human papillomavirus status of head and neck cancer as determined in cytologic specimens using the hybrid-capture 2 assay.

Oral oncology

Smith DF, Maleki Z, Coughlan D, Gooi Z, Akpeng B, Ogawa T, Bishop JA, Frick KD, Agrawal N, Gourin CG, Ha PK, Koch WM, Richmon JD, Westra WH, Pai SI

Aquaporin-1 promoter hypermethylation is associated with improved prognosis in salivary gland adenoid cystic carcinoma.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Tan M, Shao C, Bishop JA, Feng Z, Trock BJ, Westra WH, Ha PK

Transcervical Ultrasonography Is Feasible to Visualize and Evaluate Base of Tongue Cancers Imaging.

International Journal of Radiation Oncology • Biology • Physics

C. Fakhry, J. Califano, B. Messing, J. Richmon, H. Quon, G. Neuner, J. Saunders, P. Ha, M. Gillison, R. Blanco

Ultrasound in the Search for the Primary Site of Unknown Primary Head-and-Neck Squamous Cell Cancers Imaging.

International Journal of Radiation Oncology • Biology • Physics

C. Fakhry, N. Agrawal, J. Califano, S. Coquia, U. Hamper, J. Saunders, B. Messing, P. Ha, M. Gillison, R. Blanco

Transcervical ultrasonography is feasible to visualize and evaluate base of tongue cancers.

PloS one

Blanco RG, Califano J, Messing B, Richmon J, Liu J, Quon H, Neuner G, Saunders J, Ha PK, Sheth S, Gillison M, Fakhry C

Clusterin is a gene-specific target of microRNA-21 in head and neck squamous cell carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Mydlarz W, Uemura M, Ahn S, Hennessey P, Chang S, Demokan S, Sun W, Shao C, Bishop J, Krosting J, Mambo E, Westra W, Ha P, Sidransky D, Califano J

Transoral robotic surgery experience in 44 cases.

Journal of laparoendoscopic & advanced surgical techniques. Part A

Blanco RG, Fakhry C, Ha PK, Ryniak K, Messing B, Califano JA, Saunders JR

Increased Aquaporin-1 Expression Is Associated with Improved Prognosis in Salivary Gland Adenoid Cystic Carcinoma.

Otolaryngology

Marietta Tan, Chunbo Shao, Justin Bishop, William H. Westra, Patrick K. Ha

Aberrantly activated AREG-EGFR signaling is required for the growth and survival of CRTC1-MAML2 fusion-positive mucoepidermoid carcinoma cells.

Oncogene

Chen Z, Chen J, Gu Y, Hu C, Li JL, Lin S, Shen H, Cao C, Gao R, Li J, Ha PK, Kaye FJ, Griffin JD, Wu L

Abstract 655: Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma .

Molecular and cellular biology

Enrico Munari, Mariana Brait, Cynthia LeBron, Maartje G. Noordhuis, Shahnaz Begum, Christina Michailidi, Nilda Gonzalez-Roibon, Leonel Maldonado, Tanusree Sen, Rafael Guerrero-Preston, Leslie Cope, Paola Parrella, Vito Michele Fazio, Patrick K. Ha, George Netto, David Sidransky, Mohammad O. Hoque

Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma.

Cell cycle (Georgetown, Tex.)

Brait M, Munari E, LeBron C, Noordhuis MG, Begum S, Michailidi C, Gonzalez-Roibon N, Maldonado L, Sen T, Guerrero-Preston R, Cope L, Parrella P, Fazio VM, Ha PK, Netto GJ, Sidransky D, Hoque MO

In response to Objective assessment in residency-based training for transoral robotic surgery.

The Laryngoscope

Kumar R, Curry M, Ha PK, Blanco R, Califano J, Richmon J

OGDHL is a modifier of AKT-dependent signaling and NF-?B function.

PloS one

Sen T, Sen N, Noordhuis MG, Ravi R, Wu TC, Ha PK, Sidransky D, Hoque MO

Suprabasin is hypomethylated and associated with metastasis in salivary adenoid cystic carcinoma.

PloS one

Shao C, Tan M, Bishop JA, Liu J, Bai W, Gaykalova DA, Ogawa T, Vikani AR, Agrawal Y, Li RJ, Kim MS, Westra WH, Sidransky D, Califano JA, Ha PK

Salivary Preservation Using Submandibular Gland Transfer and Salivary Gland Sparing IMRT in Definitive Chemoradiation Therapy for Oropharyngeal Cancer.

International Journal of Radiation Oncology • Biology • Physics

M.S. Rutenberg, M. Tan, P. Ha, E. Zinreich, J. Saunders, R. Blanco, M. Levine, B. Messing, G. Neuner

Multidisciplinary service utilization pattern by advanced head and neck cancer patients: a single institution study.

International journal of otolaryngology

Junn JC, Kim IA, Zahurak ML, Tan M, Fan KY, Lake ST, Zaboli D, Messing BP, Ulmer K, Harrer KB, Gold D, Ryniak KL, Zinreich ES, Tang M, Levine MA, Blanco RG, Saunders JR, Califano JA, Ha PK

Robotic-assisted neck dissection through a pre- and post-auricular hairline incision: preclinical study.

Journal of laparoendoscopic & advanced surgical techniques. Part A

Blanco RG, Ha PK, Califano JA, Fakry C, Richmon J, Saunders JM

Neck dissection through a facelift incision.

The Laryngoscope

Melvin TA, Eliades SJ, Ha PK, Fakhry C, Saunders JM, Califano JA, Blanco RG

Objective assessment in residency-based training for transoral robotic surgery.

The Laryngoscope

Curry M, Malpani A, Li R, Tantillo T, Jog A, Blanco R, Ha PK, Califano J, Kumar R, Richmon J

The effect of amifostine on submandibular gland histology after radiation.

International journal of otolaryngology

Junn JC, Sciubba JJ, Bishop JA, Zinreich E, Tang M, Levine MA, Palermo RA, Fakhry C, Blanco RG, Saunders JR, Califano JA, Ha PK

Dose-dependent activation of putative oncogene SBSN by BORIS.

PloS one

Gaykalova D, Vatapalli R, Glazer CA, Bhan S, Shao C, Sidransky D, Ha PK, Califano JA

Hyperfractionated radiotherapy with concurrent cisplatin/5-Fluorouracil for locoregional advanced head and neck cancer: analysis of 105 consecutive patients.

International journal of otolaryngology

Zaboli D, Tan M, Gogineni H, Lake S, Fan K, Zahurak ML, Messing B, Ulmer K, Zinreich ES, Levine MA, Tang M, Pai SI, Blanco RG, Saunders JR, Best SR, Califano JA, Ha PK

Comparison of acute toxicities in two primary chemoradiation regimens in the treatment of advanced head and neck squamous cell carcinoma.

Annals of surgical oncology

Fan KY, Gogineni H, Zaboli D, Lake S, Zahurak ML, Best SR, Levine MA, Tang M, Zinreich ES, Saunders JR, Califano JA, Blanco RG, Pai SI, Messing B, Ha PK

Abstract 5017: DNA methylation array screening in salivary gland adenoid cystic carcinoma.

Molecular and cellular biology

Chunbo Shao, Marietta Tan, Justin A. Bishop, Ami R. Vikani, Patrick K. Ha

Molecular biology of adenoid cystic carcinoma.

Head & neck

Liu J, Shao C, Tan ML, Mu D, Ferris RL, Ha PK

Value of chest CT in the diagnosis and management of tracheobronchial foreign bodies.

Pediatrics international : official journal of the Japan Pediatric Society

Bai W, Zhou X, Gao X, Shao C, Califano JA, Ha PK

Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma.

International journal of oncology

Cho YG, Chang X, Park IS, Yamashita K, Shao C, Ha PK, Pai SI, Sidransky D, Kim MS

BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Bhan S, Negi SS, Shao C, Glazer CA, Chuang A, Gaykalova DA, Sun W, Sidransky D, Ha PK, Califano JA

Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Shao C, Sun W, Tan M, Glazer CA, Bhan S, Zhong X, Fakhry C, Sharma R, Westra WH, Hoque MO, Moskaluk CA, Sidransky D, Califano JA, Ha PK

Abstract 2042: Cancer-specific transcription factor BORIS has different effects on expression of its target genes via chromatin structure alterations.

Cellular and Molecular Biology

Daria A. Gaykalova, Chad A. Glazer, Rajita Vatapalli, Sheetal Bhan, Chunbo Shao, Patrick K. Ha, Joseph A. Califano

Abstract 4802: Cat eye syndrome chromosome region, candidate 1 (CECR1) is overexpressed and hypomethylated in salivary gland adenoid cystic carcinoma.

Cellular and Molecular Biology

Chunbo Shao, Marietta Tan, Chad A. Glazer, Sheetal Bhan, Xiaofei Chang, Mamoru Uemura, Myoung S. Kim, Christopher Moskaluk, David Sidransky, Joseph A. Califano, Patrick K. Ha

Abstract 5001: BORIS and MageA expression correlate positively in melanoma.

Cellular and Molecular Biology

Sheetal Bhan, Chunbo Shao, Hao Wang, Chad Glazer, Victor Lobanenkov, Patrick Ha, Joseph Califano

Transoral robotic surgery of the vocal cord.

Journal of laparoendoscopic & advanced surgical techniques. Part A

Blanco RG, Ha PK, Califano JA, Saunders JM

Evaluation of MYB promoter methylation in salivary adenoid cystic carcinoma.

Oral oncology

Shao C, Bai W, Junn JC, Uemura M, Hennessey PT, Zaboli D, Sidransky D, Califano JA, Ha PK

Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma.

Head & neck

Best SR, Ha PK, Blanco RG, Saunders JR, Zinreich ES, Levine MA, Pai SI, Walker M, Trachta J, Ulmer K, Murakami P, Thompson R, Califano JA, Messing BP

Mitochondrial DNA mutation in normal margins and tumors of recurrent head and neck squamous cell carcinoma patients.

Cancer prevention research (Philadelphia, Pa.)

Dasgupta S, Koch R, Westra WH, Califano JA, Ha PK, Sidransky D, Koch WM

Quantitative methylation profiles for multiple tumor suppressor gene promoters in salivary gland tumors.

PloS one

Durr ML, Mydlarz WK, Shao C, Zahurak ML, Chuang AY, Hoque MO, Westra WH, Liegeois NJ, Califano JA, Sidransky D, Ha PK

Abstract 2202: Integrated screening for epigenetically controlled tumor suppressor genes and oncogenes in salivary adenoid cystic carcinoma.

Cellular and Molecular Biology

Chunbo Shao, Wenyue Sun, Leslie Cope, Weiliang Bai, Sheetal Bhan, Xiaoli Zhong, David Sidransky, Joseph A. Califano, Christopher Moskaluk, Patrick K. Ha

Abstract 2703: Loss of dependence on EGFR signaling by upregulation of Mig6 confers drug resistance to erlotinib.

Clinical Research

Xiaofei Chang, Aditi Chatterjee, Shyhmin Huang, Myoung Sook Kim, Chunbo Shao, Constance L. Monitto, Patrick K. Ha, Manuel Hidalgo, Paul M. Harari, David M. Berman, Atul Bedi, David Sidransky

Abstract 4966: BORIS binding to the promoters of cancer testes antigens, MageA2 and MageA3, causes transcriptional activation of these genes in lung cancer.

Cellular and Molecular Biology

Sheetal Bhan, Sandeep S. Negi, Chad Glazer, Alice Chuang, Wenyue Sun, Daria Gaykalova, Chunbo Shao, Patrick K. Ha, Joseph A. Califano

Abstract 63: TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis via increased aerobic glycolysis and HIF1-alpha stabilization.

Cellular and Molecular Biology

Wenyue Sun, Yan Liu, Chad A. Glazer, Chunbo Shao, Sheetal Bhan, Semra Demokan, Ming Zhao, Michelle A. Rudek, Patrick K. Ha, Joseph A. Califano

TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.

Clinical cancer research : an official journal of the American Association for Cancer Research

Sun W, Liu Y, Glazer CA, Shao C, Bhan S, Demokan S, Zhao M, Rudek MA, Ha PK, Califano JA

Conservative management of transnasal intracranial injury.

American journal of otolaryngology

Bai W, Shao C, Sun W, Ha PK, Califano JA, Cao Z

CHAPTER 76 Biology of Head and Neck Cancer.

Cummings Otolaryngology - Head and Neck Surgery

Steven Chang, Patrick Ha

Chapter 1 Molecular Gene Alterations as Early-Detection Markers.

Ian M. Smith, Joseph A. Califano, Patrick K. Ha

Laryngeal lipoma associated with diffuse lipomatosis: case report and literature review.

Ear, nose, & throat journal

Durr ML, Agrawal N, Saunders JR, Ha PK

Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands.

PloS one

Mithani SK, Shao C, Tan M, Smith IM, Califano JA, El-Naggar AK, Ha PK

Selective versus comprehensive neck dissection after chemoradiation for advanced oropharyngeal squamous cell carcinoma.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Hillel AT, Fakhry C, Pai SI, Williams MF, Blanco RG, Zinreich ES, Levine MA, Westra WH, Saunders JR, Ha PK

Limitations of PET/CT in determining need for neck dissection after primary chemoradiation for advanced head and neck squamous cell carcinoma.

ORL; journal for oto-rhino-laryngology and its related specialties

Lyford-Pike S, Ha PK, Jacene HA, Saunders JR, Tufano RP

S1. Molecular detection strategies in OSCC.

Oral Oncology Supplement

P. Ha

Severe hypocalcemia complicating thyroid surgery after Roux-en-Y gastric bypass procedure.

Archives of otolaryngology--head & neck surgery

Durr ML, Saunders JR, Califano JA, Tufano RP, Koch WM, Ha PK

Management of early-stage laryngeal cancer.

Otolaryngologic clinics of North America

Agrawal N, Ha PK

Molecular techniques and genetic alterations in head and neck cancer.

Oral oncology

Ha PK, Chang SS, Glazer CA, Califano JA, Sidransky D

Presence of HPV DNA in convalescent salivary rinses is an adverse prognostic marker in head and neck squamous cell carcinoma.

Oral oncology

Chuang AY, Chuang TC, Chang S, Zhou S, Begum S, Westra WH, Ha PK, Koch WM, Califano JA

Downregulation of RAD17 in head and neck cancer.

Head & neck

Zhao M, Begum S, Ha PK, Westra W, Califano J

The role of positron emission tomography and computed tomography fusion in the management of early-stage and advanced-stage primary head and neck squamous cell carcinoma.

Archives of otolaryngology--head & neck surgery

Ha PK, Hdeib A, Goldenberg D, Jacene H, Patel P, Koch W, Califano J, Cummings CW, Flint PW, Wahl R, Tufano RP

Short hospital stay after neck dissection.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Ha PK, Couch ME, Tufano RP, Koch WM, Califano JA

Mitochondrial DNA quantity increases with histopathologic grade in premalignant and malignant head and neck lesions.

Clinical cancer research : an official journal of the American Association for Cancer Research

Kim MM, Clinger JD, Masayesva BG, Ha PK, Zahurak ML, Westra WH, Califano JA

Effect of human papillomavirus-16 infection on CD8+ T-cell recognition of a wild-type sequence p53264-272 peptide in patients with squamous cell carcinoma of the head and neck.

Clinical cancer research : an official journal of the American Association for Cancer Research

Sirianni N, Ha PK, Oelke M, Califano J, Gooding W, Westra W, Whiteside TL, Koch WM, Schneck JP, DeLeo A, Ferris RL

The role of human papillomavirus in oral carcinogenesis.

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists

Ha PK, Califano JA

Gene expression alterations over large chromosomal regions in cancers include multiple genes unrelated to malignant progression.

Proceedings of the National Academy of Sciences of the United States of America

Masayesva BG, Ha P, Garrett-Mayer E, Pilkington T, Mao R, Pevsner J, Speed T, Benoit N, Moon CS, Sidransky D, Westra WH, Califano J

Intraoperative molecular margin analysis in head and neck cancer.

Archives of otolaryngology--head & neck surgery

Goldenberg D, Harden S, Masayesva BG, Ha P, Benoit N, Westra WH, Koch WM, Sidransky D, Califano JA

A transcriptional progression model for head and neck cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Ha PK, Benoit NE, Yochem R, Sciubba J, Zahurak M, Sidransky D, Pevsner J, Westra WH, Califano J

Identification of putative hypermethylation-inactivated tumor suppressor genes in HNSCC.

Otolaryngology

Michael M. Kim, Patrick K. Ha, Zhongmin Guo, Nicole Benoit, Keishi Yamashita, Joseph Califano, David Sidransky

R098: Identification of Putative Hypermethylation-Inactivated Tumor Suppressor Genes in HNSCC.

Otolaryngology

Michael M Kim, Patrick K Ha, Zhongmin Guo, Nicole Benoit, Keishi Yamashita, Joseph Califano, David Sidransky

Mitochondrial DNA alterations in thyroid cancer.

Journal of surgical oncology

Tong BC, Ha PK, Dhir K, Xing M, Westra WH, Sidransky D, Califano JA

The molecular biology of mucosal field cancerization of the head and neck.

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists

Ha PK, Califano JA

Progression of microsatellite instability from premalignant lesions to tumors of the head and neck.

International journal of cancer

Ha PK, Pilkington TA, Westra WH, Sciubba J, Sidransky D, Califano JA

The molecular biology of laryngeal cancer.

Otolaryngologic clinics of North America

Ha PK, Califano JA

Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation.

Clinical cancer research : an official journal of the American Association for Cancer Research

Ha PK, Tong BC, Westra WH, Sanchez-Cespedes M, Parrella P, Zahurak M, Sidransky D, Califano JA

Oncocytic neoplasms of the parotid gland: a 16-year institutional review.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Capone RB, Ha PK, Westra WH, Pilkington TM, Sciubba JJ, Koch WM, Cummings CW

Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity.

Clinical cancer research : an official journal of the American Association for Cancer Research

Ha PK, Pai SI, Westra WH, Gillison ML, Tong BC, Sidransky D, Califano JA

BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines.

Cancer research

Wong AK, Shanahan F, Chen Y, Lian L, Ha P, Hendricks K, Ghaffari S, Iliev D, Penn B, Woodland AM, Smith R, Salada G, Carillo A, Laity K, Gupte J, Swedlund B, Tavtigian SV, Teng DH, Lees E

Osteosarcoma of the head and neck: a review of the Johns Hopkins experience.

The Laryngoscope

Ha PK, Eisele DW, Frassica FJ, Zahurak ML, McCarthy EF

Genetics of pancreatic cancer. From genes to families.

Surgical oncology clinics of North America

Hruban RH, Petersen GM, Ha PK, Kern SE

A health situation analysis in Trinidad and Tobago, 1990. The local health systems approach.

The West Indian medical journal

Patrick HA, Paul R, Nalder S